Reigning champion chaser Finian's Rainbow faces just four rivals as he returns to action in the Amlin 1965 Chase at Ascot on Saturday.
Nicky Henderson's charge won a thrilling renewal of the Champion Chase at Cheltenham in March before following up over two and a half miles in the Melling Chase at Aintree.
Paul Nicholls' Ghizao returned to form with a victory at Kempton earlier this month and he steps back up to Grade Two company, while the Nick Williams-trained For Non Stop tries to supplement his outstanding Old Roan Chase victory at Aintree last month.
Captain Chris represents Philip Hobbs, while Alan Jones' Quincy Des Pictons is the outsider of the group.
Williams expects For Non Stop to find this a tough ask as he is rated 11lb inferior to Finian's Rainbow, but will have just 4lb in hand under the race conditions.
He said: "It's a very strong race. We are not at all well in (at the weights) with Finian's Rainbow and Captain Chris in terms of official ratings so I think we're up against it.
"The trip is right for him and he is fit and well but we are just not favoured by the weights. The fact he's had a run should help him - that must be an advantage - while the soft ground shouldn't be too much of a problem for him."
Ghizao bounced back to winning form on his seasonal bow, but owner Andy Stewart is under no illusions about the task he will face in Berkshire, though he did manage to run Finian's Rainbow to two lengths in the Maghull Novices' Chase at Aintree in 2011.
Stewart said: "It's a very competitive race and we'd be up against it with Finian's Rainbow and Captain Chris. He's fresh and well, though, and he won on soft at Kempton, but I think he would have a lot to do against the champion chaser.
"He looked like being top class at one point and wasn't beaten far by Finian's Rainbow so he will take his chance and we will see whether he's a handicapper or something better."
7 March 2014Exchange rate pays dividend
Temps doubtful for Festival
Lockinge target for Tonto
Conor settles in at Cheltenham
De Bromhead sweet on Special
Epsom to honour St Nick
All set for a super Saturday
Mullins dominates JLT entries
Al and Dynaste top Ryanair field
Big two lead World possibles
Silver aiming to shine
Imperial only thought for Honeyball
Distance fears for Highland
Montiridge preps for Dubai trip
Ayr gets go-ahead
Ayr delay inspection decision
Benbulben misses Cheltenham
Card 'gut wrencher' for Tizzard
Guard stands tall for new record
Faugheen looms over Neptune field
Ballycasey stands firm in RSA
Sire spearheads Queen Mother list
Australia still in Derby shake-up
Henderson perfectly happy with Tent
Regal leads the way in Imperial
6 March 2014McNamara in 'excellent spirits'
Codd snapped up for Sea
Farm National bid in the balance
Byron all set for Aussie challenge
Ayr takes precautions
Bridgwater salutes unsung hero
Murtagh watches on at Lingfield
Mullins retains Fly supporting cast
Bittar welcomes bill amendments
Fenton cleared for Festival runners
Trip concerns sway McCoy to Fishers
Regal vies for Imperial rule
Mullins quintet in Supreme mix
Arkle has Champagne sparkle
Rizeena given dual Guineas options
5 March 2014Bailey praying for rain
Cee Bee supplemented for Champion
Sherwood leaning towards Bartlett
Module to take Queen Mother test
Cee Bee supplemented for Champion
Farr closes in on Winter repeat
Cirrus satisfies Barande-Barbe
Oscar teed up for Bumper raid
Tent 'sound' after injury scare
Sparrow in full flight
Seven shooting straight for Aintree
BHA soothes Mullins security fears
Moore frets over Sea Winter run
Hopes high for Alderwood return
Bolger to make late Gilgamboa call
Nay Never could be a Jersey boy
Guard gallops into record books
Cirrus fourth on Chantilly return
Security on Mullins' mind
Crecy takes Treve pacemaking role
More Of That ride up for grabs
Parade set to swerve Cheltenham
Upbeat Henderson monitoring Tent
Tea team not expecting miracles
4 March 2014Lad aiming to lift Wulfruna prize
Weld waits on Vigil call
Sherwood facing Dan deliberation
Coup was "satisfying", says Curley
Walsh: Annie can go the distance
Hughes at ease with Colonel
Wincanton switch for Artillery
Milan set for hurdles outing
Avenue back on road to Sandown
Fontwell abandons Wednesday card
Saviour likely to miss season
No World bid for Monksland
Braithwaite seeking Dream success