John Smith's is to end its sponsorship of the Grand National after the 2013 renewal of the race.
The beer producer has leant its support to the National since 2005 and told the Times it was a "difficult" decision to end its sponsorship of the three-day April meeting.
John Smith's spokesman David Jones said: "We will continue to be involved with the sport at other courses, including York, Newcastle and Brighton.
"The Grand National has been one of the jewels in our sponsorship crown and this decision was difficult. We will be exploring ways in which John Smith's can continue to be involved in the three-day meeting and talks with Aintree will take place in the coming months."
Aintree chairman Lord Daresbury is confident the meeting will not be short of suitors.
He said: "I'm sad about it. With a new management team in place, it comes at a bad time and puts more pressure on us all. It would naturally have been easier if John Smith's had been willing to extend the contract again, but I am completely confident the race will attract plenty of new interest.
"I genuinely believe it is a commercial decision. The image of the race has patently been a consideration, though I'm sure it was not the overriding one. I'm sure they got tremendous value out of the sponsorship and the branding exposure at the course was unprecedented."
John Smith's brand manager Karen Crowley said it was "the right time to move on" after a nine-year association with the National meeting.
She said: "We end our long association in the knowledge we have created a successful and significant sponsorship model that will serve Aintree and its new sponsors well in the future.
"We've enjoyed nine exciting years as the title sponsor of jump racing's flagship event, during which time we have seen the John Smith's Grand National achieve record TV viewing figures and attendances. However, we felt that now was the right time to move on, reflecting changes in the ale market and the development of the John Smith's brand."
31 October 2014Lady proves a champ
Dettori works Breeders' Cup magic
Day to remember for Ellison
Johnson remains under observation
Conti chasing second Charlie Hall
Terror scares Newmarket rivals
Filleule faces Champion test
Terror scares off Newmarket rivals
Sgt far from Reckless at Uttoxeter
Little King wears Down Royal crown
Nicholls goes on Charm offensive
Fishers angling for Wetherby prize
Lavelle star Bec in business
Weld out to break new ground
Osborne ready to 'roll the dice'
Dank bids to sign off on a high
Turf glory in sight for Telescope
Red Ed upbeat about Cadeaux
Aktabantay out of Breeders' Cup
Tearless secures Good Friday ticket
Overnight stay for Johnson
Crawford banks on Izzini progress
Toast could make Spencer think
Road charts route to Royal riches
Grece excels at Saint-Cloud
Hawk given Greatwood option
Hannon: Early speed key for Osaila
30 October 2014Tearless takes Lingfield honours
Johnson taken to hospital
Royal summons for Apache
Bowe takes aim at WKD bullseye
Hootenanny 'smoking' for BC mission
Avenue roads lead to Newmarket
Shu to be kept busy
Scu sweet on Sensation Ascot raid
Murtagh succumbs to Cup charms
Dandino to stay in Australia
Glance denied Mackinnon defence
Bailey ace rules Supreme at Taunton
O'Brien hit by Magician blow
Diablo in big-race picture
Buckley raises Toast to Osborne
Pastille seeking four-timer
Conti all set for Charlie Hall
Barnes out to storm Saint-Cloud
Williams issues Buywise warning
Lynam reveals Slade stalls fears
29 October 2014Lame Magician out of Breeders' Cup
Diablo in big-race picture
Mullins enters strong Hennessy team
Damaged hock behind Estid reverse
Eckhart team rocked by injury blow
Hunt Ball makes Power play
Morgiana a T bone of contention
Kirby ponders Buttons French raid
Glance camp turn to Williams
Wohler trusts 'professional' Moore
Red alert to Cup challenge
Head targets more Mile glory
Mile hope Toronado in 'great form'
Telescope camp banking on Moore
Twiston-Davies link excites Moore
Flying third to Bob on hurdling bow
Harden to test top staying waters
Godolphin take share in Belardo
Mullins has big guns at Down Royal
Annacotty set for Kempton return
Powell and Bradley cleared
28 October 2014Fingal camp on weather watch
More injury woe for Popham
Dickin unveils Thomas gameplan
Power stalls in Flemington spin
Toast drawn nine in BC Classic
My Ambivalent passed fit by vets
Harry out to bring House down
Three and easy for ton-up Hanagan
Wood carves out Galway verdict
More Of That in Wetherby frame
Big guns confirmed for Charlie Hall
Byron pencilled in for Far East