Paul Nicholls will be seeking a fourth success in the Betfred Becher Chase at Aintree in the last 10 years as he saddles Join Together.
The seven-year-old was third in the Mildmay Novices' Chase at the track in April and was down the field on his return at Ascot last month.
Nicholls said: "Join Together is in good form. I was a bit disappointed with him at Ascot but hopefully with different fences and a different day, he will do better. I don't think he is particularly well handicapped but he will probably be suited by the fences and, if he is, I will give him an entry in the National."
David Pipe saddles two runners, with Swing Bill and Problema Tic flying the flag for Pond House.
Swing Bill was a winner at Cheltenham last time and finished 10th in the National last season, while Problema Tic was fifth in a Grade Three event at Prestbury Park on his return.
"Swing Bill ran in the race last year (when pulled up) and is not getting any younger. But he ran in the National and seems to like Aintree, although I wouldn't want the ground too soft for him," said Pipe.
"Problema Tic is another who does not want conditions too soft. I was pleased with him at Cheltenham on his comeback."
Big Fella Thanks will be having just his second start for Tom George as he has another crack at the National fences. The 10-year-old was fourth in the 2010 Grand National when trained by Nicholls and seventh a year later when handled by Ferdy Murphy.
He was off the track after that outing until unseating Paddy Brennan in a veterans' chase on the Mildmay course.
George said: "It didn't quite go to plan last time, but maybe that was to our benefit as he is still off the same handicap mark. He's been round there a few times now so he can certainly jump the fences, but I don't think he quite gets home over the National trip. Three miles two furlongs will probably suit him better."
29 March 2017Mr Clarkson motors to Sedgefield success for David Pipe
Gold Cup ace Robbie Power appointed retained jockey for Alan and Ann Potts
Treaty Of Rome a topical winner at Southwell in Derek Shaw double
Supreme hero Labaik set for Aintree Sale at Grand National meeting
Mutakayyef likely to head straight to Royal Ascot after Dubai effort
Willie Mullins duo at head of weights for Topham Chase at Aintree
Appleby sets sights on Newmarket redemption for Jungle Cat after Dubai defeat
Carolinae on course for Finals Day date at Lingfield
Joseph O'Brien considering Guineas prep for Intricately
Simon Dow weighing up options for Qatar winner Mr Scaramanga
Charlie Longsdon's Snow Leopardess in the hunt for Fairyhouse gold
Magical Memory set to defend York title on seasonal reappearance
Derby entrant Count Octave up and running at Wolverhampton
Le Mercurey to tackle National in Party Politics colours of Patricia Thompson
Evan Williams outlines Bet365 Gold Cup plan for Buywise
Barry Geraghty awaits scan results to determine Aintree fate
Jane Chapple-Hyam to link up with Michelle Payne for Kaspersky venture
Henry Candy happy to sit tight with Limato after Dubai disappointment
Neil King says Punchestown is 'Plan A' for Lil Rockerfeller
Michael Bell in no rush to map out seasonal gameplan with Big Orange
Nick Williams keen for Flying Tiger to earn his stripes in Aintree Grade One
28 March 2017Hattons Hill hits the heights again at Hexham
Former champion jockey Seb Sanders takes work-rider role with Charlie Appleby
Jeremy Gask delays retirement plans for Royal Ascot-bound Medicean Man
Mick Channon rates Naas winner Czabo 'a cracking broodmare prospect'
Willie Mullins to send small squad to Aintree
Gevrey Chambertin one of four stars to bow out for David Pipe
Brian Ellison's Tonto and Walker primed for Lincoln challenge at Doncaster
Jonjo O'Neill's Box Office puts up winning display at Market Rasen
Davy Russell booked by Tom George for Saint Are Grand National mount
Warren Greatrex maps out Aintree aims for Keeper Hill and La Bague Au Roi
Richard Johnson pays tribute to 'fantastic' Reve De Sivola
Arctic Fire pencilled in for Champion date at Punchestown
Roger Varian looking to Coronation Cup for Postponed redemption
Arrogate takes a break as Breeders' Cup repeat remains ultimate goal
27 March 2017Ex-jockey Allan Mackay in hospital after fall on Newmarket gallops
Morando among Lincoln acceptors for Roger Varian
Toscanini joins Richard Fahey to act as Ribchester's pacemaker
End of an era as Ballymacoll dispersal sales announced by Tattersalls
Flying start for Aidan O'Brien as new Irish Flat season kicks off at Naas
Aidan O'Brien targets Dundalk comeback for unbeaten Classic hope Caravaggio
Sam Twiston-Davies and Paul Nicholls dominate at Wincanton
Anseanachai Cliste prevails in Ulster National thriller at Downpatrick
In-form Noel Fehily eager to take National chance on Blaklion
Park Express delight for Mick Channon and Graham Lee with Czabo
Mark Walsh to have Cheltenham injury progress assessed
Meade readies Aclaim for Lockinge bid
Martyn Meade has Craven Stakes in mind for Classic contender Eminent
26 March 2017Brendan Brackan back in style for Irish Lincolnshire victory
Moonlight Bay shows smart turn of foot to take Irish Flat season opener
Seeyouatmidnight called up for National service by 'delighted' Sandy Thomson
Saint-Cloud scorer Plumatic one to watch
Super Solow on the comeback trail for Freddy Head
'I can't believe he won' - Bob Baffert in awe of World Cup hero Arrogate
Snow Leopardess pounces at Newbury
Jack Hobbs oozes class in Sheema stroll
Death of three-time Long Walk hero Reve De Sivola at Kelso
Moreira advertises skills in saddle as Vivlos claims Turf
Biscuits swoops for sweet success in Golden Shaheen
Right result for French ace in Al Quoz as Limato struggles
Snow digs deep for UAE Derby glory
Vazirabad does it again in Dubai Gold Cup