Tidal Bay has been ruled out of the Argento Chase at Cheltenham after failing to recover from the setback he suffered earlier this week.
The enigmatic 12-year-old was found to be slightly lame after work on Thursday morning, but after diagnosing the problem as pus in a foot, champion trainer Paul Nicholls described his chances of running as "50-50" on Friday morning.
In the absence of the sidelined Bobs Worth, last month's Lexus Chase hero was set to go off favourite for today's recognised Cheltenham Gold Cup trial, but he will not be lining up at Prestbury Park.
Nicholls later confirmed the Hennessy Gold Cup at Leopardstown on February 9 as a possible alternative for Tidal Bay.
He told Channel 4 Racing's The Morning Line: "It's a shame as it's the perfect race for him (today), but with horses, it's never that easy. He worked on Thursday morning and pulled up a little bit sore.
"He's a lot better according to Clifford (Baker, head lad) but not fit enough to run.
"He's in the Irish Hennessy and if he came together quickly in the next few days we could look at that.
"Other than that, we'll aim for Cheltenham and Aintree with him."
Outsider Calgary Bay is also a non-runner in the Argento Chase, taken out by trainer Mick Channon due to the ground.
1 August 2015Times targets Stewards' consolation
Hughes reflects on a golden career
Warrior books Ebor ticket
Muthmir makes amends
Hughes at his best on Bay
Mile proves golden for Beloved
Malabar stamps her class
Dettori guides Dubday to landmark
Charlton so Close to historic win
Diamonds ready to sparkle in Nassau
31 July 2015Pacy Muthmir rules in King George
Breizh bids for Galway glory
Pharoah Phan Phestival good to go
Jack's the lad in Galway Hurdle
Gosden salutes 'magical' Sir Peter
Laviniad gets up late in Corrib
Simple for Beckett and Bentley
Orange pips Goodwood rivals
Shalaa dazzles in Richmond
Relief for Hughes as Gibeon strikes
Cover up for Goodwood defence
30 July 2015Clown gets serious at Galway
Eddery aiming for Mile high
Fox finale for Hughes
Ivory unveils strong Stewards' team
Treacy sent for scans
Stars on show in Nassau
Lynam 'proud' of Sir Peter alliance
Tributes pour in for O'Sullevan
It's Shanahan's turn at Galway
Sir Peter O'Sullevan dies, aged 97
Kachy not for catching in Molecomb
No Sussex regrets for O'Brien
Solow flying high at Goodwood
Highland reels in Gordon rivals
Shalaa in top trim for Richmond
Dunlop excited by Trip to Goodwood
29 July 2015Fortune favours Twiston-Davies
Peacock pair vie for Galway glory
Moviesta gets King George go-ahead
Karakontie has Deauville date
Dog delivers for Mullins and Walsh
Tint proves Topaz jewel
Maguire back in the saddle
Blue back with a bang
Tough Toormore takes Lennox glory
All roads lead to Arc for Postponed
Logan shines for Kirby
Frankie grabs Gold at Goodwood
So seeking Sussex success