Connections of Captain Americo have targeted the Betfred Eider Chase at Newcastle ever since he finished second in the Borders National at Kelso in December.
Third in last year's Eider, his trainer James Ewart is hoping for another solid performance.
"He's in good form and we're very happy with him. This race has been the plan since he ran in the Borders National," said the Langholm handler.
"He doesn't run well back to back quickly. He needs large gaps between his races and this seemed a sensible opportunity."
Tom George took Desperate Dex out of the race at the final declaration stage but will be represented by Monsieur Cadou. The eight-year-old has not run since winning at Haydock in November, but that does not worry the Slad trainer.
"We were really pleased with his last run at Haydock and we've sat tight with him since then. This race has been the plan for a while," said George.
"The way he was staying on at Haydock suggests the trip will suit him well and he does seem to have found improvement since tackling extreme distances. He's 7lb out of the handicap, but the jockey takes off 7lb. The ground shouldn't be a problem for him and we're looking forward to it."
Mortimers Cross defeated Captain Americo when winning the Borders National and his owner/trainer John Needham has his fingers crossed the 12-year-old can put behind him a disappointing run at Ffos Las on Boxing Day.
The Ludlow handler said: "We're hoping he runs well. He seems fine and he's not been out since Boxing Day, when he was disappointing. It may have been the ground, or perhaps that run came too soon after Kelso.
"We are keeping our fingers crossed and Andrew Thornton, who rode him at Fontwell, said we should run him in the Eider. We are doing that and Andrew is on him, so we are hoping for the best."
21 November 2014McCoy: Landmark swayed judgment
Jacob warms up with brace
Hill peaking for Troytown return
Billy back on winning track
Walsh back for Ferof ride
New ready for Haydock Rush
Cheltenham is Big aim
Mullins eager for Faugheen run
Geraghty snapped up for Seuil
Cue primed for Betfair defence
Volnay aiming for quick repeat
Argocat camp play it cool
Leading Light retired
Frankel filly breaks Irish record
Linton loses Listed place
Doubles for Pipe and Scudamore
Nasty spill for Insole
McCoy targets midweek return
Farm comes Home to roost at Thurles
Flemenstar future dictated by scan
Cue lined up for Haydock return
20 November 2014McNamara joy at turning pro
Volnay seeking Mersey paradise
Sloane Avenue books Dubai date
Spencer reveals Qatar riding snub
Doyle ready for Godolphin challenge
Good news at Huntingdon
BHA hear Linton case
Avenue shows winning way
Grugy diagnosed with hip issue
Meade plots Monksland comeback
Ptit secures swift double
Shanes shines in hurdles win
Mullins' stars set for weekend runs
Haydock aim for Aurore
Medermit in Betfair contention
19 November 2014Shaneshill sparkles on hurdles bow
O'Grady keen on Becher run
High hopes for Zaidiyn
Cyclone makes Thurles return
Betfair launch National Jockey Day
Risk set for Haydock return
Murphy back at Navan for Troytown
Ground key to Aubusson Haydock bid
Knock A Hand in Troytown contention
Vautour given Navan entry
Place Hennessy bid excites King
That pleases in Newbury spin
Ascot aim for Master
Clouds primed for Hennessy bid
Challow option for Games
December aim for Berlais
Fenton facing Turf Club verdict
18 November 2014Nephew in Hennessy mix
Three runners for Sandra Hughes
Kempton first for Cladocera
Hobbs seeking Hennessy gold
Easy possible for quick return
Modest Moore strives for perfection
Driving ban for Queally
Meade bemused by Wood demise
Warrior no soft touch in Hennessy
Heron angling for Kempton honours
Able Deputy delivers at Plumpton
Mullins heavyweights in at Ascot
One and only on Mersey beat
Cue takes aim at Haydock double
Re set for second hurdles run